Irit Alkalay

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

Thomas Henkel, Thomas Machleidt, Irit Alkalay et al. · Nature · 1993 · 1.1K citations

Inflammation, Transcriptional Regulation, Signal Transduction +14

Axin-mediated CKI phosphorylation of β-catenin at Ser 45: a molecular switch for the Wnt pathway

Sharon Amit, Ada Hatzubai, Yaara Birman et al. · Genes & Development · 2002 · 766 citations · Full text

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

Jong‐Dae Lee, Ji‐Hun Mo, Kyoko Katakura et al. · Nature Cell Biology · 2006 · 601 citations

Inflammation, Signal Transduction, Mucosal Immunology +11

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.

Irit Alkalay, Avraham Yaron, Ada Hatzubai et al. · Proceedings of the National Academy of Sciences · 1995 · 440 citations · Full text

Molecular Regulation, Proteasome, Cell Death +16

Redox regulation of a protein tyrosine kinase in the endoplasmic reticulum

Asne R. Bauskin, Irit Alkalay, Yinon Ben‐Neriah · Cell · 1991 · 240 citations

Redox Signaling, Signal Transduction, Biochemistry +12