Concepedia
Statistics
Publications
13
Citations
1.1K
H-Index
12
Active since
1990
Affiliations
Takeda (United States)(Current)
Millennium Engineering and Integration (United States)
Stanford University
Paul D. Greenspan is an author at Takeda (United States) specializing in pharmacology, medicine, and drug discovery.
Top concepts
PharmacologyMedicineDrug DiscoveryDrug DevelopmentBiomolecular EngineeringPharmacotherapyMedicinal ChemistryChemistryBiochemistryNatural Sciences
Publications per year
1990–2021
A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment
Marc L. Hyer, Michael A. Milhollen, Jeff Ciavarri et al. · Nature Medicine · 2018 · 414 citations
Medicine, Anti-cancer Agent, Small-molecule Inhibitor +8
Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer
Steven Langston, Stephen Grossman, Dylan B. England et al. · Journal of Medicinal Chemistry · 2021 · 194 citations · Full text
Identification of Dipeptidyl Nitriles as Potent and Selective Inhibitors of Cathepsin B through Structure-Based Drug Design
Paul D. Greenspan, Kirk Clark, Rubén Tommasi et al. · Journal of Medicinal Chemistry · 2001 · 136 citations · Full text
An unusual oxidative cyclization. A synthesis and absolute stereochemical assignment of (-)-rocaglamide
Barry M. Trost, Paul D. Greenspan, Bingwei Yang et al. · Journal of the American Chemical Society · 1990 · 103 citations
Unusual Oxidative Cyclization, Engineering, Heterocyclic +12
A Total Synthesis of ( + )‐2′<i>S</i>, 3′<i>R</i>‐Zoapatanol
Barry M. Trost, Paul D. Greenspan, Jung Ho Kim · Angewandte Chemie International Edition in English · 1994 · 41 citations
Cross-coupling Reaction, Engineering, Wacker Oxidation +11
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