Norbert Hoefgen

In Vivo Efficacy in Airway Disease Models of N-(3,5-Dichloropyrid-4-yl)-[1-(4-fluorobenzyl)-5-hydroxy-indole-3-yl]-glyoxylic Acid Amide (AWD 12-281), a Selective Phosphodiesterase 4 Inhibitor for Inhaled Administration

Hildegard Kuss, Norbert Hoefgen, Sarah Johanssen et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 89 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Highly Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitors

Michael S. Malamas, Yike Ni, James Erdei et al. · Journal of Medicinal Chemistry · 2011 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Effect of PDE10A inhibitors on MK-801-induced immobility in the forced swim test

Barbara Langen, Rita Dost, Ute Egerland et al. · Psychopharmacology · 2011 · 36 citations

Medicine, Pharmacology, Experimental Pharmacology +2

Novel triazines as potent and selective phosphodiesterase 10A inhibitors

Michael S. Malamas, Hans Stange, Rudolf Schindler et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Synthesis and structure–activity relationship studies of dihydronaphthyridinediones as a novel structural class of potent and selective PDE7 inhibitors

Rainer Gewald, C. RUEGER, Christian Grunwald et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11