Concepedia

In Vivo Efficacy in Airway Disease Models of N-(3,5-Dichloropyrid-4-yl)-[1-(4-fluorobenzyl)-5-hydroxy-indole-3-yl]-glyoxylic Acid Amide (AWD 12-281), a Selective Phosphodiesterase 4 Inhibitor for Inhaled Administration

Hildegard Kuss, Norbert Hoefgen, Sarah Johanssen, Thomas Kronbach, Chris Rundfeldt

Journal of Pharmacology and Experimental Therapeutics · 2003 · 89 citations · 20 references

DOI

Concepts

References

20

Chronic Obstructive Pulmonary Disease

Peter J. Barnes · New England Journal of Medicine · 2000 · 1.1K citations

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Anti-Inflammatory and Immunomodulatory Potential of the Novel PDE4 Inhibitor Roflumilast in Vitro

Armin Hatzelmann, Christian Schudt · Journal of Pharmacology and Experimental Therapeutics · 2001 · 398 citations

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In Vivo Efficacy in Airway Disease Models of Roflumilast, a Novel Orally Active PDE4 Inhibitor

Daniela S. Bundschuh, Manfrid Eltze, Johannes Barsig et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 239 citations

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Cilomilast, a selective phosphodiesterase-4 inhibitor for treatment of patients with chronic obstructive pulmonary disease: a randomised, dose-ranging study

C.H. Compton, Jason Gubb, Richard Nieman et al. · The Lancet · 2001 · 210 citations

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Allergens and endotoxin on mothers' mattresses and total immunoglobulin E in cord blood of neonates

Joachim Heinrich, Gabriele Bolte, Bernd Hölscher et al. · European Respiratory Journal · 2002 · 197 citations · Full text

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