Thomas Kronbach

Cyclosporine metabolism in human liver: Identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs

Thomas Kronbach, Volker Fischer, Urs Meyer · Clinical Pharmacology & Therapeutics · 1988 · 540 citations

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

Thomas Kronbach, Daniel Mathys, Makoto Umeno et al. · Molecular Pharmacology · 1989 · 534 citations

High-performance liquid chromatographic assays for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

Thomas Kronbach, Daniel Mathys, Josef Gut et al. · Analytical Biochemistry · 1987 · 262 citations

Health Sciences, Biochemistry, Medicine +14

The molecular mechanisms of two common polymorphisms of drug oxidation-evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation

Urs Meyer, J. Gut, Thomas Kronbach et al. · Xenobiotica · 1986 · 130 citations

Drug Oxidation-evidence, Metabolomic Profiling, Common Polymorphisms +17

Debrisoquine/sparteine-type polymorphism of drug oxidation. Purification and characterization of two functionally different human liver cytochrome P-450 isozymes involved in impaired hydroxylation of the prototype substrate bufuralol.

J. Gut, Therese Catin, Pierre Dayer et al. · Journal of Biological Chemistry · 1986 · 111 citations · Full text

Secondary Metabolite, Debrisoquine/sparteine-type Polymorphism, Redox Biology +18