Therese Catin

High-performance liquid chromatographic assays for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

Thomas Kronbach, Daniel Mathys, Josef Gut et al. · Analytical Biochemistry · 1987 · 262 citations

Medicine, Biochemistry, Pharmacology +17

The molecular mechanisms of two common polymorphisms of drug oxidation-evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation

Urs Meyer, J. Gut, Thomas Kronbach et al. · Xenobiotica · 1986 · 130 citations

Medicine, Biochemistry, Pharmacology +17

Debrisoquine/sparteine-type polymorphism of drug oxidation. Purification and characterization of two functionally different human liver cytochrome P-450 isozymes involved in impaired hydroxylation of the prototype substrate bufuralol.

J. Gut, Therese Catin, Pierre Dayer et al. · Journal of Biological Chemistry · 1986 · 111 citations · Full text

Medicine, Biochemistry, Pharmacology +16

Debrisoquine‐type polymorphism of drug oxidation: purification from human liver of a cytochrome P450 isozyme with high activity for bufuralol hydroxylation

J. Gut, Robin B. Gasser, Pierre Dayer et al. · FEBS Letters · 1984 · 55 citations

Medicine, Biochemistry, Pharmacology +16

Mephenytoin-type polymorphism of drug oxidation: purification and characterization of a human liver cytochrome P-450 isozyme catalyzing microsomal mephenytoin hydroxylation

Josef Gut, U. Thomas Meier, Therese Catin et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 1986 · 27 citations

Medicine, Biochemistry, Pharmacology +17