Michael S. Malamas

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

Mei-Chu Lo, Ann Aulabaugh, Guixian Jin et al. · Analytical Biochemistry · 2004 · 675 citations

Drug Target, Engineering, Hit Identification +11

Evaluation of an Estrogen Receptor-β Agonist in Animal Models of Human Disease

Heather A. Harris, Leo Albert, Yelena Leathurby et al. · Endocrinology · 2003 · 312 citations · Full text

Estrogen Action, Pharmacotherapy, Female Reproductive Function +16

Quinazolineacetic acids and related analogs as aldose reductase inhibitors

Michael S. Malamas, Jane Millen · Journal of Medicinal Chemistry · 1991 · 275 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Aldo-keto Reductase +16

Phosphodiesterase 10A Inhibitor Activity in Preclinical Models of the Positive, Cognitive, and Negative Symptoms of Schizophrenia

Steven M. Grauer, Virginia Pulito, Rachel L. Navarra et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 265 citations

Design and Synthesis of Aryl Diphenolic Azoles as Potent and Selective Estrogen Receptor-β Ligands

Michael S. Malamas, Eric S. Manas, Robert McDevitt et al. · Journal of Medicinal Chemistry · 2004 · 259 citations · Full text

Combinatorial Chemistry, Organic Chemistry, Pharmacotherapy +19