Roni Chau

Statistics

Publications

Citations

580

H-Index

Active since

2021

Affiliations

Denali Therapeutics (United States)(Current)

University of Minnesota

Biogen (United States)

University of California, San Francisco

Roni Chau is an author at Denali Therapeutics (United States) specializing in neuroscience, blood-brain barrier delivery, and blood-brain barrier penetration.

ORCID

Publications per year

2021–2025

Publications

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Todd Logan, Matthew Simon, Gerald Maxwell Cherf et al. · Cell · 2021 · 229 citations · Full text

Life Sciences, Genetics, Neuroscience +12

Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia

Dan Xia, Steve Lianoglou, Thomas Sandmann et al. · Molecular Neurodegeneration · 2022 · 123 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme

Annie Arguello, Cathal Mahon, Meredith Calvert et al. · The Journal of Experimental Medicine · 2021 · 84 citations · Full text

Pharmacy, Neuroscience, Pharmaceutics +17

Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution

Nathalie Khoury, Michelle E. Pizzo, Claire B. Discenza et al. · Nature Communications · 2025 · 50 citations · Full text

Pharmacy, Neuroscience, Pharmaceutics +16

Transferrin receptor–targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA

Michelle E. Pizzo, Edward D. Plowey, Nathalie Khoury et al. · Science · 2025 · 44 citations

Pharmacy, Neuroscience, Pharmaceutics +17

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