Satoru Kohgo

4′-Ethynyl Nucleoside Analogs: Potent Inhibitors of Multidrug-Resistant Human Immunodeficiency Virus Variants In Vitro

Eiichi Kodama, Satoru Kohgo, Kenji Kitano et al. · Antimicrobial Agents and Chemotherapy · 2001 · 135 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

2′-Deoxy-4′-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants

Atsushi Kawamoto, Eiichi Kodama, Stefan G. Sarafianos et al. · The International Journal of Biochemistry & Cell Biology · 2008 · 125 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Activity against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine

Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh et al. · Antimicrobial Agents and Chemotherapy · 2007 · 103 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Syntheses of 4<i>‘</i><i>-</i><i>C</i>-Ethynyl-β-<scp>d</scp>-<i>arabino- </i>and 4‘-<i>C-</i>Ethynyl-2<i>‘</i>-deoxy-β-<scp>d</scp>-<i>ribo-</i>pentofuranosylpyrimidines and -purines and Evaluation of Their Anti-HIV Activity

Hiroshi Ohrui, Satoru Kohgo, Kenji Kitano et al. · Journal of Medicinal Chemistry · 2000 · 84 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +15

2′-Deoxy-4′-<i>C</i>-Ethynyl-2-Fluoroadenosine: A Nucleoside Reverse Transcriptase Inhibitor with Highly Potent Activity Against Wide Spectrum of HIV-1 Strains, Favorable Toxic Profiles, and Stability in Plasma

Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa et al. · Nucleosides Nucleotides & Nucleic Acids · 2007 · 54 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17