Stefan G. Sarafianos

Crystal structure of HIV‐1 reverse transcriptase in complex with a polypurine tract RNA:DNA

Stefan G. Sarafianos, Kalyan Das, Chris Tantillo et al. · The EMBO Journal · 2001 · 407 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody fab fragment at 2.8 Å resolution

Jianping Ding, Kalyan Das, Y. Hsiou et al. · Journal of Molecular Biology · 1998 · 322 citations

Life Sciences, Biochemistry, Molecular Biology +15

Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids

Stefan G. Sarafianos, Kalyan Das, Arthur D. Clark et al. · Proceedings of the National Academy of Sciences · 1999 · 306 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Molecular Modeling and Biochemical Characterization Reveal the Mechanism of Hepatitis B Virus Polymerase Resistance to Lamivudine (3TC) and Emtricitabine (FTC)

Kalyan Das, Xiao‐Feng Xiong, Huiling Yang et al. · Journal of Virology · 2001 · 275 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability

A.T. Gres, Karen A. Kirby, Vineet N. KewalRamani et al. · Science · 2015 · 260 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17