Masayuki Amano

Potent Inhibition of HIV-1 Replication by Novel Non-peptidyl Small Molecule Inhibitors of Protease Dimerization

Yasuhiro Koh, Shintaro Matsumi, Debananda Das et al. · Journal of Biological Chemistry · 2007 · 149 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Activity against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine

Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh et al. · Antimicrobial Agents and Chemotherapy · 2007 · 103 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

<i>In Vitro</i> Selection of Highly Darunavir-Resistant and Replication-Competent HIV-1 Variants by Using a Mixture of Clinical HIV-1 Isolates Resistant to Multiple Conventional Protease Inhibitors

Yasuhiro Koh, Masayuki Amano, Tomomi Towata et al. · Journal of Virology · 2010 · 93 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Design and Synthesis of Potent HIV-1 Protease Inhibitors Incorporating Hexahydrofuropyranol-Derived High Affinity P₂ Ligands: Structure−Activity Studies and Biological Evaluation

Arun K. Ghosh, Bruno D. Chapsal, Abigail Baldridge et al. · Journal of Medicinal Chemistry · 2010 · 71 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

A Novel Bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI), GRL-98065, Is Potent against Multiple-PI-Resistant Human Immunodeficiency Virus In Vitro

Masayuki Amano, Yasuhiro Koh, Debananda Das et al. · Antimicrobial Agents and Chemotherapy · 2007 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17