Bruno D. Chapsal

Total Synthesis of Enantiopure (+)-γ-Lycorane Using Highly Efficient Pd-Catalyzed Asymmetric Allylic Alkylation

Bruno D. Chapsal, Iwao Ojima · Organic Letters · 2006 · 85 citations · Full text

Key Step, Cross-coupling Reaction, Engineering +13

Design and Synthesis of Potent HIV-1 Protease Inhibitors Incorporating Hexahydrofuropyranol-Derived High Affinity P₂ Ligands: Structure−Activity Studies and Biological Evaluation

Arun K. Ghosh, Bruno D. Chapsal, Abigail Baldridge et al. · Journal of Medicinal Chemistry · 2010 · 71 citations · Full text

Catalytic asymmetric transformations with fine-tunable biphenol-based monodentate ligands

Bruno D. Chapsal, Zihao Hua, Iwao Ojima · Tetrahedron Asymmetry · 2006 · 46 citations

Engineering, Catalytic Asymmetric Transformations, Organic Chemistry +4

Design of HIV-1 Protease Inhibitors with C3-Substituted Hexahydrocyclopentafuranyl Urethanes as P2-Ligands: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Structure

Arun K. Ghosh, Bruno D. Chapsal, Garth L. Parham et al. · Journal of Medicinal Chemistry · 2011 · 36 citations · Full text

Bioorganic Chemistry, C3-substituted Hexahydrocyclopentafuranyl Urethanes, Antiviral Drug +17

Novel HIV-1 Protease Inhibitors (PIs) Containing a Bicyclic P2 Functional Moiety, Tetrahydropyrano-Tetrahydrofuran, That Are Potent against Multi-PI-Resistant HIV-1 Variants

Kazuhiko Ide, Manabu Aoki, Masayuki Amano et al. · Antimicrobial Agents and Chemotherapy · 2011 · 26 citations · Full text