Garth L. Parham

Highly Potent HIV-1 Protease Inhibitors with Novel Tricyclic P2 Ligands: Design, Synthesis, and Protein–Ligand X-ray Studies

Arun K. Ghosh, Garth L. Parham, Cuthbert D. Martyr et al. · Journal of Medicinal Chemistry · 2013 · 46 citations · Full text

Antiviral Drug, Chemical Biology, Pharmaceutical Chemistry +16

Design of HIV-1 Protease Inhibitors with C3-Substituted Hexahydrocyclopentafuranyl Urethanes as P2-Ligands: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Structure

Arun K. Ghosh, Bruno D. Chapsal, Garth L. Parham et al. · Journal of Medicinal Chemistry · 2011 · 36 citations · Full text

Bioorganic Chemistry, C3-substituted Hexahydrocyclopentafuranyl Urethanes, Antiviral Drug +17

Latent Warheads for Targeted Cancer Therapy: Design and Synthesis of pro-Pyrrolobenzodiazepines and Conjugates

Iontcho R. Vlahov, Longwu Qi, Paul J. Kleindl et al. · Bioconjugate Chemistry · 2017 · 15 citations

A Novel Tricyclic Ligand-Containing Nonpeptidic HIV-1 Protease Inhibitor, GRL-0739, Effectively Inhibits the Replication of Multidrug-Resistant HIV-1 Variants and Has a Desirable Central Nervous System Penetration Property <i>In Vitro</i>

Masayuki Amano, Yasushi Tojo, Pedro Miguel Salcedo-Gómez et al. · Antimicrobial Agents and Chemotherapy · 2015 · 11 citations · Full text