Yasushi Tojo

Structural and Molecular Interactions of CCR5 Inhibitors with CCR5

Kenji Maeda, Debananda Das, Hiromi Ogata-Aoki et al. · Journal of Biological Chemistry · 2006 · 161 citations · Full text

Ccr5 Involvement, Immunology, Antiviral Drug +16

<i>In Vitro</i> Selection of Highly Darunavir-Resistant and Replication-Competent HIV-1 Variants by Using a Mixture of Clinical HIV-1 Isolates Resistant to Multiple Conventional Protease Inhibitors

Yasuhiro Koh, Masayuki Amano, Tomomi Towata et al. · Journal of Virology · 2010 · 92 citations · Full text

Hiv-1 Resistance, Immunology, Molecular Biology +18

Prediction of Potency of Protease Inhibitors Using Free Energy Simulations with Polarizable Quantum Mechanics-Based Ligand Charges and a Hybrid Water Model

Debananda Das, Yasuhiro Koh, Yasushi Tojo et al. · Journal of Chemical Information and Modeling · 2009 · 78 citations · Full text

Design, Synthesis, Protein−Ligand X-ray Structure, and Biological Evaluation of a Series of Novel Macrocyclic Human Immunodeficiency Virus-1 Protease Inhibitors to Combat Drug Resistance

Arun K. Ghosh, Sarang Kulkarni, David D. Anderson et al. · Journal of Medicinal Chemistry · 2009 · 42 citations · Full text

GRL-0519, a Novel Oxatricyclic Ligand-Containing Nonpeptidic HIV-1 Protease Inhibitor (PI), Potently Suppresses Replication of a Wide Spectrum of Multi-PI-Resistant HIV-1 Variants <i>In Vitro</i>

Masayuki Amano, Yasushi Tojo, Pedro Miguel Salcedo-Gómez et al. · Antimicrobial Agents and Chemotherapy · 2013 · 28 citations · Full text

Immunology, Molecular Biology, Wide Spectrum +18