Fernando G. Osorio

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

Fernando G. Osorio, Claire Navarro, Juan Cadiñanos et al. · Science Translational Medicine · 2011 · 409 citations · Full text

Sclerostin, Anti-aging, Aging +18

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

Ignacio Varela, Sandrine Pereira, Alejandro P. Ugalde et al. · Nature Medicine · 2008 · 392 citations · Full text

Lifespan Extension, Human Premature, Aging +12

An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells

Sarah Bowling, Duluxan Sritharan, Fernando G. Osorio et al. · Cell · 2020 · 327 citations · Full text

Lineage Histories, Off-target Effect, Simultaneous Readout +10

Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response

Fernando G. Osorio, Clea Bárcena, Clara Soria‐Valles et al. · Genes & Development · 2012 · 269 citations · Full text

Aging, Anti-aging, Nuclear Lamina +26

Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis

Fernando G. Osorio, Axel Rosendahl Huber, Rurika Oka et al. · Cell Reports · 2018 · 241 citations · Full text