Alejandro P. Ugalde

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9

Gözde Korkmaz, Rui Lopes, Alejandro P. Ugalde et al. · Nature Biotechnology · 2016 · 419 citations

Enhancer Elements, Engineering, Cell Modification +12

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

Ignacio Varela, Sandrine Pereira, Alejandro P. Ugalde et al. · Nature Medicine · 2008 · 392 citations · Full text

Lifespan Extension, Human Premature, Aging +12

Tumour-specific proline vulnerability uncovered by differential ribosome codon reading

Fabricio Loayza‐Puch, Koos Rooijers, Levi C.M. Buil et al. · Nature · 2016 · 276 citations · Full text

Tumor Biology, Tumour-specific Proline Vulnerability, Medicine +5

Aging and chronic DNA damage response activate a regulatory pathway involving miR‐29 and p53

Alejandro P. Ugalde, Andrew Ramsay, Jorge de la Rosa et al. · The EMBO Journal · 2011 · 255 citations · Full text

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

Jesús Espada, Ignacio Varela, Ignacio Flores et al. · The Journal of Cell Biology · 2008 · 162 citations · Full text