Rui Lopes

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9

Gözde Korkmaz, Rui Lopes, Alejandro P. Ugalde et al. · Nature Biotechnology · 2016 · 419 citations

Enhancer Elements, Engineering, Cell Modification +12

Tumour-specific proline vulnerability uncovered by differential ribosome codon reading

Fabricio Loayza‐Puch, Koos Rooijers, Levi C.M. Buil et al. · Nature · 2016 · 276 citations · Full text

Tumor Biology, Tumour-specific Proline Vulnerability, Medicine +5

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA

Nicolas Léveillé, Carlos A. Melo, Koos Rooijers et al. · Nature Communications · 2015 · 195 citations · Full text

p53 induces transcriptional and translational programs to suppress cell proliferation and growth

Fabricio Loayza‐Puch, Jarno Drost, Koos Rooijers et al. · Genome biology · 2013 · 117 citations · Full text

PAX8 and MECOM are interaction partners driving ovarian cancer

Melusine Bleu, Fanny Mermet‐Meillon, Verena Apfel et al. · Nature Communications · 2021 · 77 citations · Full text