Xiangyi Jiang

Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles

Boshi Huang, Wen‐Ming Chen, Tong Zhao et al. · Journal of Medicinal Chemistry · 2019 · 76 citations · Full text

Contemporary Medicinal Chemistry Strategies for the Discovery and Development of Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

Zhao Wang, Srinivasulu Cherukupalli, Minghui Xie et al. · Journal of Medicinal Chemistry · 2022 · 61 citations · Full text

Medicinal Chemistry, Biochemistry, Potent Nnrtis +15

Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors

Xiangyi Jiang, Gaochan Wu, Waleed A. Zalloum et al. · RSC Advances · 2019 · 55 citations · Full text

In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBP

Dongwei Kang, Da Feng, Lanlan Jing et al. · European Journal of Medicinal Chemistry · 2020 · 30 citations

Antiviral Compound, Natural Sciences, Human Retrovirus +12

Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp3 values and favorable drug-like properties

Xiangyi Jiang, Boshi Huang, Fisayo A. Olotu et al. · European Journal of Medicinal Chemistry · 2020 · 26 citations · Full text

Medicinal Chemistry, High Fsp3 Values, Medicine +11