Publication | Open Access

Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp3 values and favorable drug-like properties

Medicinal ChemistryHigh Fsp3 ValuesMedicineNatural SciencesAntiviral Drug DevelopmentMolecular BiologyTolerant RegionResistance Mutation (Virology)Antiviral DrugHivPharmacologyAntiviral CompoundPotent Hiv-1 NnrtisDrug Discovery