Dongwei Kang

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling

Yi Zheng, Meng-Wei Zhuang, Lulu Han et al. · Signal Transduction and Targeted Therapy · 2020 · 296 citations · Full text

Design, Synthesis, and Evaluation of Thiophene[3,2-<i>d</i>]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles

Dongwei Kang, Zengjun Fang, Zhenyu Li et al. · Journal of Medicinal Chemistry · 2016 · 134 citations · Full text

New techniques and strategies in drug discovery

Jintong Du, Jing Guo, Dongwei Kang et al. · Chinese Chemical Letters · 2020 · 109 citations

Medicinal Chemistry, Drug Target, Hit Identification +6

Structure-Based Optimization of Thiophene[3,2-<i>d</i>]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants

Dongwei Kang, Zengjun Fang, Boshi Huang et al. · Journal of Medicinal Chemistry · 2017 · 91 citations · Full text

Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus

Ye Tian, Zhaoqiang Liu, Jinghan Liu et al. · European Journal of Medicinal Chemistry · 2018 · 91 citations · Full text

Medicine, Antiviral Drug Development, Entrance Channel +9