Zengjun Fang

Design, Synthesis, and Evaluation of Thiophene[3,2-<i>d</i>]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles

Dongwei Kang, Zengjun Fang, Zhenyu Li et al. · Journal of Medicinal Chemistry · 2016 · 135 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure-Based Optimization of Thiophene[3,2-<i>d</i>]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants

Dongwei Kang, Zengjun Fang, Boshi Huang et al. · Journal of Medicinal Chemistry · 2017 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

Peng Zhan, Xinyong Liu, Junjie Zhu et al. · Bioorganic & Medicinal Chemistry · 2009 · 87 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies

Peng Zhan, Xinyong Liu, Zhenyu Li et al. · Bioorganic & Medicinal Chemistry · 2009 · 87 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-Based Bioisosterism Yields HIV-1 NNRTIs with Improved Drug-Resistance Profiles and Favorable Pharmacokinetic Properties

Dongwei Kang, Da Feng, Yanying Sun et al. · Journal of Medicinal Chemistry · 2020 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17