Deping Chai

Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells

Julia Billiard, Jennifer B. Dennison, Jacques Briand et al. · Cancer & Metabolism · 2013 · 231 citations · Full text

3-(1,1-Dioxo-2<i>H</i>-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1<i>H</i>)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase

Rosanna Tedesco, Antony N. Shaw, Ramesh Bambal et al. · Journal of Medicinal Chemistry · 2006 · 159 citations · Full text

Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295

Xiangping Qian, Andrew McDonald, Han-Jie Zhou et al. · ACS Medicinal Chemistry Letters · 2010 · 64 citations · Full text

Molecular Biology, New Generation, Cancer Biology +19

An efficient, asymmetric solid-phase synthesis of benzothiadiazine-substituted tetramic acids: Potent inhibitors of the hepatitis C virus RNA-dependent RNA polymerase

Karen A. Evans, Deping Chai, Todd L. Graybill et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 44 citations · Full text

Asymmetric Solid-phase Synthesis, Biochemistry, Antiviral Therapy +6

Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase

Antony N. Shaw, Rosanna Tedesco, Ramesh Bambal et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 44 citations · Full text

Medicine, Antiviral Drug Development, Hepatitis +6