Concepedia
Statistics
Publications
18
Citations
1.2K
H-Index
15
Active since
1991
Affiliations
GlaxoSmithKline (United States)(Current)
New Frontier
South College
Carlsberg Laboratory
Research Triangle Park Foundation
Jacques Briand is an author at GlaxoSmithKline (United States) specializing in drug discovery, life sciences, and pharmacology.
Publications per year
1991–2022
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia
Melissa B. Pappalardi, Kathryn Keenan, Mark Cockerill et al. · Nature Cancer · 2021 · 280 citations · Full text
Medicine, Oncology, Pharmacology +8
Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells
Julia Billiard, Jennifer B. Dennison, Jacques Briand et al. · Cancer & Metabolism · 2013 · 238 citations · Full text
Life Sciences, Medicinal Chemistry, Pharmacology +16
Design of potent and selective human cathepsin K inhibitors that span the active site
Scott K. Thompson, Stacie M. Halbert, Mary J. Bossard et al. · Proceedings of the National Academy of Sciences · 1997 · 119 citations
Life Sciences, Biochemistry, Pharmacology +17
A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site
Mary Ann Hardwicke, Alan R. Rendina, Shawn P. Williams et al. · Nature Chemical Biology · 2014 · 108 citations · Full text
Life Sciences, Biochemistry, Molecular Biology +10
Development of a fully automated multichannel peptide synthesizer with an integrated TFA cleavage capability
J. Neimark, Jacques Briand · Peptides · 1994 · 91 citations
Pharmacy, Biotechnology, Synthetic Biology +3
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