Karen A. Evans

Efficient one-pot preparation of 5-substituted-2-amino-1,3,4-oxadiazoles using resin-bound reagents

Frank T. Coppo, Karen A. Evans, Todd L. Graybill et al. · Tetrahedron Letters · 2004 · 112 citations

Pharmacy, Medicinal Chemistry, Synthetic Medicinal Chemistry +7

Discovery of 3-Aryl-4-isoxazolecarboxamides as TGR5 Receptor Agonists

Karen A. Evans, Brian Budzik, Sean Ross et al. · Journal of Medicinal Chemistry · 2009 · 75 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity

N.O. Concha, Angela Smallwood, William G. Bonnette et al. · Molecular Pharmacology · 2015 · 54 citations

Life Sciences, Biochemistry, Molecular Biology +16

Synthesis and structure–activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists

Brian Budzik, Karen A. Evans, David D. Wisnoski et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

An efficient, asymmetric solid-phase synthesis of benzothiadiazine-substituted tetramic acids: Potent inhibitors of the hepatitis C virus RNA-dependent RNA polymerase

Karen A. Evans, Deping Chai, Todd L. Graybill et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +16