Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure

Fady I. Malik, James J. Hartman, Kathleen A. Elias, +31

Science

Cardiac MuscleHeart FailureCardiovascular PharmacologyCytoskeletonMechanotransduction +18

Antitumor activity of an allosteric inhibitor of centromere-associated protein-E

Kenneth W. Wood, Latesh Lad, Lusong Luo, +32

Proceedings of the National Academy of Sciences

Antitumor ActivityCenp-e Motor ActivityMolecular BiologyCell DeathCytoskeleton +16

Controlling Mammalian Cell Spreading and Cytoskeletal Arrangement with Conveniently Fabricated Continuous Wavy Features on Poly(dimethylsiloxane)

Xingyu Jiang, Shuichi Takayama, Xiangping Qian, +6

Langmuir

Cell Contact GuidanceEngineeringBiomimetic MaterialsMicroscopyCell Adhesion +24

Discovery of<i>Omecamtiv Mecarbil</i>the First, Selective, Small Molecule Activator of Cardiac Myosin

B. Paul Morgan, Alexander R. Muci, Pu‐Ping Lu, +25

ACS Medicinal Chemistry Letters

Arrays of Self-Assembled Monolayers for Studying Inhibition of Bacterial Adhesion

Xiangping Qian, Steven J. Metallo, Insung S. Choi, +3

Analytical Chemistry

Molecular docking, molecular dynamics simulation, and structure-based 3D-QSAR studies on estrogenic activity of hydroxylated polychlorinated biphenyls

Xiaolin Li, Li Ye, Xiaoxiang Wang, +5

The Science of The Total Environment

Combinatorial ChemistryEstrogenic ActivityMedicinal ChemistryEngineeringBiochemistry +7

Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295

Xiangping Qian, Andrew McDonald, Han-Jie Zhou, +46

ACS Medicinal Chemistry Letters

Molecular BiologyNew GenerationCancer BiologyPharmaceutical ChemistryMedicinal Chemistry +17

Enzyme-Controlled Intracellular Self-Assembly of ¹⁸F Nanoparticles for Enhanced MicroPET Imaging of Tumor

Yaling Liu, Qingqing Miao, Pei Zou, +7

Theranostics

NanoparticlesNanotherapeuticsEngineeringBiomedical EngineeringRadioactive Nanoparticles +20

Highly selective inhibition of myosin motors provides the basis of potential therapeutic application

Serena Sirigu, James J. Hartman, Vicente J. Planelles-Herrero, +13

Proceedings of the National Academy of Sciences

GLYCOSYLTRANSFERASES IN OLIGOSACCHARIDE SYNTHESIS

Xiangping Qian, Keiko Sujino, Monica M. Palcic, +1

Journal of Carbohydrate Chemistry

BiologyBiosynthesisBioorganic ChemistryBiochemistryMicroscopy +11