Pu‐Ping Lu

Discovery of<i>Omecamtiv Mecarbil</i>the First, Selective, Small Molecule Activator of Cardiac Myosin

B. Paul Morgan, Alexander R. Muci, Pu‐Ping Lu et al. · ACS Medicinal Chemistry Letters · 2010 · 112 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

One-Step, Stereocontrolled Synthesis of Glycosyl 1-Phosphates, Uridine-5‘-diphosphogalactose, and Uridine-5‘-diphosphoglucose from Unprotected Glycosyl Donors

Stephen Hanessian, Pu‐Ping Lu, Hideki Ishida · Journal of the American Chemical Society · 1998 · 46 citations

Pharmacy, Biochemistry, Carbohydrate Chemistry +16

Highly selective inhibition of myosin motors provides the basis of potential therapeutic application

Serena Sirigu, James J. Hartman, Vicente J. Planelles-Herrero et al. · Proceedings of the National Academy of Sciences · 2016 · 40 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +16

An Enzyme-Bound Bisubstrate Hybrid Inhibitor of Adenylosuccinate Synthetase

Stephen Hanessian, Pu‐Ping Lu, Jean‐Yves Sancéau et al. · Angewandte Chemie International Edition · 1999 · 39 citations

Pharmacy, Biochemistry, Medicinal Chemistry +7

Discovery of<i>Tirasemtiv</i>, the First Direct Fast Skeletal Muscle Troponin Activator

Scott E. Collibee, Gustave Bergnes, Alexander R. Muci et al. · ACS Medicinal Chemistry Letters · 2018 · 30 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +8