Marina Pliushchev

The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex

Yupeng He, Sujatha Selvaraju, Michael L. Curtin et al. · Nature Chemical Biology · 2017 · 229 citations · Full text

Protein Function, Signal Transduction, Molecular Regulation +7

Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a

Ramzi F. Sweis, Marina Pliushchev, Peter J. Brown et al. · ACS Medicinal Chemistry Letters · 2014 · 185 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +18

The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia

William N. Pappano, Jun Guo, Yupeng He et al. · PLoS ONE · 2015 · 92 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +17

Discovery and Metabolic Stabilization of Potent and Selective 2-Amino-<i>N</i>-(adamant-2-yl) Acetamide 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors

Jeffrey J. Rohde, Marina Pliushchev, Bryan K. Sorensen et al. · Journal of Medicinal Chemistry · 2006 · 76 citations · Full text

Medicinal Chemistry, Pharmacological Study, Biochemistry +11

The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class

Richard J. Sciotti, Marina Pliushchev, Paul E. Wiedeman et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 60 citations · Full text

Antifungal Agent, Bioorganic Chemistry, Novel Series +9