Peter J. Brown

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Steven A. Kliewer, Scott S. Sundseth, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 1997 · 2.1K citations · Full text

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

H. Eric Xu, Millard H. Lambert, Valerie G. Montana et al. · Molecular Cell · 1999 · 1.2K citations · Full text

Metabolic Syndrome, Lipid Synthesis, Biochemistry +1

The promise and peril of chemical probes

C.H. Arrowsmith, James E. Audia, Christopher P. Austin et al. · Nature Chemical Biology · 2015 · 836 citations · Full text

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Masoud Vedadi, Dalia Baršytė-Lovejoy, Feng Liu et al. · Nature Chemical Biology · 2011 · 527 citations

Signal Transduction, Cellular Enzymology, Biochemistry +12

An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

Kyle D. Konze, Anqi Ma, Fengling Li et al. · ACS Chemical Biology · 2013 · 464 citations · Full text

Histone Modifications, Epigenetic Change, Molecular Biology +20