Bryan K. Sorensen

2,4-Diarylpyrrolidine-3-carboxylic AcidsPotent ET_A Selective Endothelin Receptor Antagonists. 1. Discovery of A-127722

Martin Winn, Thomas W von Geldern, Terry J. Opgenorth et al. · Journal of Medicinal Chemistry · 1996 · 113 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 4. Side Chain Conformational Restriction Leads to ET_B Selectivity

Thomas W von Geldern, Andrew S. Tasker, Bryan K. Sorensen et al. · Journal of Medicinal Chemistry · 1999 · 90 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery and Metabolic Stabilization of Potent and Selective 2-Amino-<i>N</i>-(adamant-2-yl) Acetamide 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors

Jeffrey J. Rohde, Marina Pliushchev, Bryan K. Sorensen et al. · Journal of Medicinal Chemistry · 2006 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Adamantane sulfone and sulfonamide 11-β-HSD1 Inhibitors

Bryan K. Sorensen, Martin Winn, Jeff Rohde et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 64 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +3

Imidazo[2,1-b]thiazoles: Multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases

Steve Fidanze, Scott Erickson, Gary T. Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 56 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14