Andrew S. Tasker

AMG 706, an Oral, Multikinase Inhibitor that Selectively Targets Vascular Endothelial Growth Factor, Platelet-Derived Growth Factor, and Kit Receptors, Potently Inhibits Angiogenesis and Induces Regression in Tumor Xenografts

Anthony Polverino, Angela Coxon, Charlie Starnes et al. · Cancer Research · 2006 · 283 citations · Full text

Tumor Xenografts, Pharmacotherapy, Tumor Biology +19

TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation

Yi-Hung Ou, Michael J. Torres, Rosalyn Ram et al. · Molecular Cell · 2011 · 227 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +7

Systematic Study of the Glutathione (GSH) Reactivity of<i>N</i>-Arylacrylamides: 1. Effects of Aryl Substitution

Victor J. Cee, Laurie P. Volak, Yuping Chen et al. · Journal of Medicinal Chemistry · 2015 · 149 citations

c-Met Inhibitors with Novel Binding Mode Show Activity against Several Hereditary Papillary Renal Cell Carcinoma-related Mutations

Steven F. Bellon, Paula Kaplan‐Lefko, Yajing Yang et al. · Journal of Biological Chemistry · 2007 · 137 citations · Full text

2,4-Diarylpyrrolidine-3-carboxylic AcidsPotent ET_A Selective Endothelin Receptor Antagonists. 1. Discovery of A-127722

Martin Winn, Thomas W von Geldern, Terry J. Opgenorth et al. · Journal of Medicinal Chemistry · 1996 · 110 citations · Full text

Combinatorial Chemistry, Molecular Pharmacology, Medicinal Chemistry +12