Thomas W von Geldern

Novel <i>p</i>-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 2. Mechanism of Inhibition and Structure-Based Improvement of Pharmaceutical Properties

Gang Liu, Jeffrey R. Huth, Edward T. Olejniczak et al. · Journal of Medicinal Chemistry · 2001 · 354 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Discovery of Novel <i>p</i>-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 1. Identification of an Additional Binding Pocket Based on an Anilino Diaryl Sulfide Lead

Gang Liu, J. T. Link, Zhonghua Pei et al. · Journal of Medicinal Chemistry · 2000 · 218 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.

Terry J. Opgenorth, Andrew Adler, Samuel V. Calzadilla et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 210 citations

Medicine, Pharmacology, Physiology +15

Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin‐mediated angioedema

Ryan M. Fryer, Jason A. Segreti, Patricia N. Banfor et al. · British Journal of Pharmacology · 2007 · 131 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +10

2,4-Diarylpyrrolidine-3-carboxylic AcidsPotent ET_A Selective Endothelin Receptor Antagonists. 1. Discovery of A-127722

Martin Winn, Thomas W von Geldern, Terry J. Opgenorth et al. · Journal of Medicinal Chemistry · 1996 · 113 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17