Amy King

Establishing <i>in vitro in vivo</i> correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics

Lindsay B. Avery, Jason Wade, Mengmeng Wang et al. · mAbs · 2017 · 97 citations · Full text

Immunocytochemical Technique, Immunology, Pathology +21

Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer

Adam Root, Wei Cao, Bilian Li et al. · Antibodies · 2016 · 92 citations · Full text

Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics

Nicole Piche‐Nicholas, Lindsay B. Avery, Amy King et al. · mAbs · 2017 · 74 citations · Full text

High‐throughput measurement, correlation analysis, and machine‐learning predictions for pH and thermal stabilities of Pfizer‐generated antibodies

Amy King, Matthew Woods, Wei Liu et al. · Protein Science · 2011 · 66 citations · Full text

Peptide Science, Analytical Ultracentrifugation, Protein Folding +21

Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design

James R. Apgar, Amy Tam, Rhady Sorm et al. · PLoS ONE · 2020 · 48 citations · Full text

Engineering, Negative Charge Patches, Biomedical Engineering +20