Mengmeng Wang

Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies

Lindsay B. Avery, Mengmeng Wang, Mania Kavosi et al. · mAbs · 2016 · 107 citations · Full text

Immunocytochemical Technique, Transgenic Mouse Models, Immunology +18

Establishing <i>in vitro in vivo</i> correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics

Lindsay B. Avery, Jason Wade, Mengmeng Wang et al. · mAbs · 2017 · 97 citations · Full text

Immunocytochemical Technique, Immunology, Pathology +21

Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics

Nicole Piche‐Nicholas, Lindsay B. Avery, Amy King et al. · mAbs · 2017 · 74 citations · Full text

One Mouse, One Pharmacokinetic Profile: Quantitative Whole Blood Serial Sampling for Biotherapeutics

Alison Joyce, Mengmeng Wang, Rosemary F. Lawrence-Henderson et al. · Pharmaceutical Research · 2014 · 53 citations

Therapeutic Drug Monitoring, Pharmacokinetic Profile, Medicine +7

Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics

Tetsuya Ishino, Mengmeng Wang, Lidia Mosyak et al. · Journal of Biological Chemistry · 2013 · 45 citations · Full text