Mania Kavosi

Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies

Lindsay B. Avery, Mengmeng Wang, Mania Kavosi et al. · mAbs · 2016 · 107 citations · Full text

Immunocytochemical Technique, Transgenic Mouse Models, Immunology +18

Establishing <i>in vitro in vivo</i> correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics

Lindsay B. Avery, Jason Wade, Mengmeng Wang et al. · mAbs · 2017 · 97 citations · Full text

Immunocytochemical Technique, Immunology, Pathology +21

Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics

Nicole Piche‐Nicholas, Lindsay B. Avery, Amy King et al. · mAbs · 2017 · 74 citations · Full text

Bioanalytical platform comparison using a generic human IgG PK assay format

Beth Leary, Rosemary F. Lawrence-Henderson, Mireia Fernández Ocaña et al. · Journal of Immunological Methods · 2013 · 34 citations

Engineering, Medicine, Bioanalysis +14

Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing

Yan Weng, Tetsuya Ishino, Annette Sievers et al. · Scientific Reports · 2018 · 29 citations · Full text