Jason Wade

Establishing <i>in vitro in vivo</i> correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics

Lindsay B. Avery, Jason Wade, Mengmeng Wang et al. · mAbs · 2017 · 102 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions

William J.J. Finlay, Orla Cunningham, Matthew Lambert et al. · Journal of Molecular Biology · 2009 · 64 citations

Pharmacy, Immunology, Antibody Engineering +15

Comprehensive Interrogation of a Minimalist Synthetic CDR-H3 Library and Its Ability to Generate Antibodies with Therapeutic Potential

Ciara M. Mahon, Matthew Lambert, Jacob Glanville et al. · Journal of Molecular Biology · 2013 · 50 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +14

Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies

Brian J. Fennell, James R. Apgar, Matthew Lambert et al. · Proceedings of the National Academy of Sciences · 2015 · 25 citations · Full text

Pharmacy, Biotechnology, Immunology +17

Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors

Adam Root, Gurkan Guntas, Madan Katragadda et al. · mAbs · 2021 · 17 citations · Full text

Pharmacy, Immunology, Oncology +17