Eric W. Scocchera

Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents

Behnoush Hajian, Eric W. Scocchera, Carolyn Shoen et al. · Cell chemical biology · 2019 · 66 citations · Full text

Pulmonary Tuberculosis, Drug Target, Biochemistry +11

Palladium‐Catalyzed <i>N</i>‐Demethylation/<i>N</i>‐Acylation of Some Morphine and Tropane Alkaloids

Robert J. Carroll, Hannes Leisch, Eric W. Scocchera et al. · Advanced Synthesis & Catalysis · 2008 · 46 citations

Medicinal Chemistry, Various N ‐Acyl, Engineering +13

Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes

Kishore Viswanathan, Kathleen M. Frey, Eric W. Scocchera et al. · PLoS ONE · 2012 · 38 citations · Full text

Soft Tissue Infections, Bioorganic Chemistry, Antibiotic Adjuvant +25

Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens

Eric W. Scocchera, Stephanie M. Reeve, Santosh Keshipeddy et al. · ACS Medicinal Chemistry Letters · 2016 · 36 citations · Full text

Classical Antifolates, Bioorganic Chemistry, Molecular Biology +19

Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations

Stephanie M. Reeve, Eric W. Scocchera, Jacob Ferreira et al. · Journal of Medicinal Chemistry · 2016 · 31 citations · Full text

Promising Lead Series, Molecular Biology, Antimicrobial Chemotherapy +17