Stephanie M. Reeve

Protein design algorithms predict viable resistance to an experimental antifolate

Stephanie M. Reeve, Pablo Gaínza, Kathleen M. Frey et al. · Proceedings of the National Academy of Sciences · 2014 · 52 citations · Full text

Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in <i>S</i>. <i>aureus</i>

Santosh Keshipeddy, Stephanie M. Reeve, Amy C. Anderson et al. · Journal of the American Chemical Society · 2015 · 38 citations · Full text

Wild-type Dhfr, Molecular Biology, Antimicrobial Chemotherapy +25

A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance

Dmitry Leshchiner, Federico Rosconi, Bharathi Sundaresh et al. · Nature Communications · 2022 · 38 citations · Full text

Bacteria Evade Antibiotics, Genome-wide Atlas, Health Sciences +12

Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens

Eric W. Scocchera, Stephanie M. Reeve, Santosh Keshipeddy et al. · ACS Medicinal Chemistry Letters · 2016 · 36 citations · Full text

Classical Antifolates, Bioorganic Chemistry, Molecular Biology +19

Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations

Stephanie M. Reeve, Eric W. Scocchera, Jacob Ferreira et al. · Journal of Medicinal Chemistry · 2016 · 31 citations · Full text

Promising Lead Series, Molecular Biology, Antimicrobial Chemotherapy +17