Martin Carroll

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

Patrick S. Ward, Jay Patel, David R. Wise et al. · Cancer Cell · 2010 · 2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

Ly Vu, Brian F. Pickering, Yuanming Cheng et al. · Nature Medicine · 2017 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Thomas Farge, Estelle Saland, Fabienne de Toni et al. · Cancer Discovery · 2017 · 916 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

Omar Abdel‐Wahab, Mazhar Adli, Lindsay M. LaFave et al. · Cancer Cell · 2012 · 590 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Single-cell mutation analysis of clonal evolution in myeloid malignancies

Linde A. Miles, Robert L. Bowman, Tiffany R. Merlinsky et al. · Nature · 2020 · 529 citations · Full text

Medicine, Molecular Biology, Oncology +16