Kathy Hsiao

Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme

Yong Gu, Keisuke Kuida, Hiroko Tsutsui et al. · Science · 1997 · 1.1K citations

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan et al. · Nature · 2016 · 893 citations

Cancer Research, Allosteric Inhibition, Signal Transduction +12

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

James P Griffith, Joseph L. Kim, Eunice E Kim et al. · Cell · 1995 · 835 citations · Full text

X-ray Crystallography, Protein Chemistry, Protein Function +7

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Silvia Buonamici, Juliet Williams, Michael Morrissey et al. · Science Translational Medicine · 2010 · 553 citations

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

Keith P. Wilson, Patricia G. McCaffrey, Kathy Hsiao et al. · Chemistry & Biology · 1997 · 275 citations · Full text

Drug Target, P38 Map Kinase, Biochemistry +10