J. Michael Wardleworth

ICI 125,211: A new gastric antisecretory agent acting on histamine H2-receptors

Tobias O. Yellin, Stephen H. Buck, D. Gilman et al. · Life Sciences · 1979 · 97 citations

Ici 125,211, Medicine, Immunology +6

Cellular pharmacology and in vivo activity of a new anticancer agent, ZD9331: a water-soluble, nonpolyglutamatable, quinazoline-based inhibitor of thymidylate synthase.

Ann L. Jackman, Rosemary Kimbell, G. Wynne Aherne et al. · PubMed · 1997 · 92 citations

Thymidylate Synthase, Cellular Pharmacology, Chemical Biology +17

Quinazoline antifolate thymidylate synthase inhibitors: heterocyclic benzoyl ring modifications

Peter R. Marsham, Leslie R. Hughes, Ann L. Jackman et al. · Journal of Medicinal Chemistry · 1991 · 78 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Heterocyclic +12

Design and Synthesis of Potent Non-Polyglutamatable Quinazoline Antifolate Thymidylate Synthase Inhibitors

Peter R. Marsham, J. Michael Wardleworth, F. Thomas Boyle et al. · Journal of Medicinal Chemistry · 1999 · 46 citations · Full text

Combinatorial Chemistry, Organic Chemistry, Pharmacotherapy +16

Synthesis and Structure‐Activity Relationships of a Novel Antifungal Agent, ICI 195,739

F. Thomas Boyle, D. Gilman, Michael B. Gravestock et al. · Annals of the New York Academy of Sciences · 1988 · 37 citations

Bioorganic Chemistry, Enzyme Complex, Antimicrobial Chemotherapy +18