Peter R. Marsham

Quinazoline antifolate thymidylate synthase inhibitors: heterocyclic benzoyl ring modifications

Peter R. Marsham, Leslie R. Hughes, Ann L. Jackman et al. · Journal of Medicinal Chemistry · 1991 · 78 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Heterocyclic +12

Quinazoline antifolate thymidylate synthase inhibitors: alkyl, substituted alkyl, and aryl substituents in the C-2 position

Leslie R. Hughes, Ann L. Jackman, J.W. Oldfield et al. · Journal of Medicinal Chemistry · 1990 · 73 citations · Full text

Discovery and Optimization of a Series of Carbazole Ureas as NPY5 Antagonists for the Treatment of Obesity

M. Block, Scott Boyer, Wayne Brailsford et al. · Journal of Medicinal Chemistry · 2002 · 65 citations · Full text

Component Aniline, Medicinal Chemistry, Biochemistry +15

Design and Synthesis of Potent Non-Polyglutamatable Quinazoline Antifolate Thymidylate Synthase Inhibitors

Peter R. Marsham, J. Michael Wardleworth, F. Thomas Boyle et al. · Journal of Medicinal Chemistry · 1999 · 46 citations · Full text

Combinatorial Chemistry, Organic Chemistry, Pharmacotherapy +16

The measurement of polyglutamate metabolites of the thymidylate synthase inhibitoR, ICI D1694, in mouse and human cultured cells

William Gibson, Graham M. F. Bisset, Peter R. Marsham et al. · Biochemical Pharmacology · 1993 · 35 citations

Biochemistry, Medicine, Biochemical Genetics +8