Graham M. F. Bisset

Novel prodrugs which are activated to cytotoxic alkylating agents by carboxypeptidase G2

Caroline J. Springer, Pari Antoniw, Bagshawe et al. · Journal of Medicinal Chemistry · 1990 · 134 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Partial syntheses of optically pure methyl bacteriopheophorbides c and d from methyl pheophorbide a

Kevin M. Smith, Graham M. F. Bisset, Michael J. Bushell · The Journal of Organic Chemistry · 1980 · 72 citations

Natural Sciences, Chemistry, Bioisosterism +4

Mechanism of photooxidation of bacteriochlorophyll c derivatives. A possible model for natural chlorophyll breakdown.

Stanley B. Brown, Kevin M. Smith, Graham M. F. Bisset et al. · Journal of Biological Chemistry · 1980 · 47 citations · Full text

Life Sciences, Biochemistry, Chemistry +15

The measurement of polyglutamate metabolites of the thymidylate synthase inhibitoR, ICI D1694, in mouse and human cultured cells

William Gibson, Graham M. F. Bisset, Peter R. Marsham et al. · Biochemical Pharmacology · 1993 · 36 citations

Life Sciences, Biochemistry, Pharmacology +10

Syntheses and thymidylate synthase inhibitory activity of the poly-.gamma.-glutamyl conjugates of N-[5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2-thenoyl]-L-glutamic acid (ICI D1694) and other quinazoline antifolates

Graham M. F. Bisset, Krzysztof Pawełczak, Ann L. Jackman et al. · Journal of Medicinal Chemistry · 1992 · 34 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7