Andreas Gollner

Drugging an undruggable pocket on KRAS

Dirk Kessler, Michael Gmachl, Andreas Mantoulidis et al. · Proceedings of the National Academy of Sciences · 2019 · 434 citations · Full text

Medicine, Molecular Biology, Oncology +15

Regioselective reactions for programmable resveratrol oligomer synthesis

Scott A. Snyder, Andreas Gollner, Maria Chiriac · Nature · 2011 · 206 citations · Full text

Pharmacy, Chemical Engineering, Catalysis +12

Targeting cancer with small-molecule pan-KRAS degraders

Johannes Popow, William Farnaby, Andreas Gollner et al. · Science · 2024 · 158 citations · Full text

Medicine, Medicinal Chemistry, Oncology +15

Discovery of Novel Spiro[3<i>H</i>-indole-3,2′-pyrrolidin]-2(1<i>H</i>)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2–p53 Interaction

Andreas Gollner, Dorothea Rudolph, Heribert Arnhof et al. · Journal of Medicinal Chemistry · 2016 · 121 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS ^G12C Inhibitor

Joachim Bröker, Alex G. Waterson, Chris A. Smethurst et al. · Journal of Medicinal Chemistry · 2022 · 81 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16