Wonsuk Chang

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Publications

Citations

2.8K

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Active since

2001

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

PharmaSeq (United States)

Johns Hopkins University

Princeton University

United States Military Academy

Wonsuk Chang is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in pharmacology, medicinal chemistry, and antiviral pharmacology.

ORCID

Publications per year

2001–2024

Publications

An orally available non-nucleotide STING agonist with antitumor activity

Bo‐Sheng Pan, Samanthi A. Perera, Jennifer Piesvaux et al. · Science · 2020 · 660 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Discovery of a β-<scp>d</scp>-2′-Deoxy-2′-α-fluoro-2′-β-<i>C</i>-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus

Michael J. Sofia, Donghui Bao, Wonsuk Chang et al. · Journal of Medicinal Chemistry · 2010 · 620 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977

Eisuke Murakami, Tatiana Tolstykh, Haiying Bao et al. · Journal of Biological Chemistry · 2010 · 293 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer

Wonsuk Chang, Michael D. Altman, Charles A. Lesburg et al. · Journal of Medicinal Chemistry · 2022 · 137 citations · Full text

Pharmacy, Oncology, Pharmacology +17

A kinase-cGAS cascade to synthesize a therapeutic STING activator

John A. McIntosh, Zhijian Liu, Brian M. Andresen et al. · Nature · 2022 · 135 citations

Life Sciences, Molecular Biology, Pharmacology +10

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