Wonsuk Chang - Concepedia

Author

Wonsuk Chang

Merck & Co., Inc., Rahway, NJ, USA (United States)ORCID

Also Known As

Chang, Wonsuk, W.-S. W. Chang, Won-Suk Chang, Wonsuk Chang, Won‐Suk Chang

Publications

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)PharmaSeq (United States)Johns Hopkins University Princeton University United States Military Academy

About

Wonsuk Chang is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	18	19	2.5K
2	Biochemistry	10	10	1.3K
3	Natural Sciences	9	9	1.2K
4	Engineering	2	2	59
5	Applied Physics	1	1	14

Wonsuk Chang

Publications

2.7K

Citations

H-Index

Page 1

	Year	Citations
Discovery of a β-<scp>d</scp>-2′-Deoxy-2′-α-fluoro-2′-β-<i>C</i>-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus Michael J. Sofia, Donghui Bao, Wonsuk Chang, Journal of Medicinal Chemistry Viral Polymerase StructureHepatitis C VirusMolecular BiologyAntiviral DrugHcv Therapies	2010	613
An orally available non-nucleotide STING agonist with antitumor activity Bo‐Sheng Pan, Samanthi A. Perera, Jennifer Piesvaux, Science Antitumor ActivityImmunologyImmunoeditingImmunologic MechanismPharmacotherapy	2020	609
Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977 Eisuke Murakami, Tatiana Tolstykh, Haiying Bao, Journal of Biological Chemistry BiochemistryFirst StepViral HepatitisNatural SciencesMedicine	2010	288
A kinase-cGAS cascade to synthesize a therapeutic STING activator John A. McIntosh, Zhijian Liu, Brian M. Andresen, Nature Signal TransductionBiochemistryReceptor Tyrosine KinaseKinase-cgas CascadeVenomics	2022	125
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer Wonsuk Chang, Michael D. Altman, Charles A. Lesburg, Journal of Medicinal Chemistry ImmunologyMolecular BiologyInterferon GenesImmunotherapyTumor Biology	2022	122
Effect of artemisinins and other endoperoxides on nitric oxide-related signaling pathway in RAW 264.7 mouse macrophage cells V. Badireenath Konkimalla, Martina Blunder, Bernhard Korn, Nitric Oxide InflammationReactive Nitrogen SpecieCell SignalingMedicineLipid Peroxidation	2008	99
From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9 Whitney L. Petrilli, Gregory C. Adam, Roman S. Erdmann, Cell chemical biology BiochemistryMedicineNatural SciencesPeptide LibrarySmall Molecule Ligands	2019	80
Malaria-Infected Mice Are Cured by a Single Dose of Novel Artemisinin Derivatives Gary H. Posner, Ik‐Hyeon Paik, Wonsuk Chang, Journal of Medicinal Chemistry Combinatorial ChemistryPharmaceutical ScienceAntiparasitic AgentMalariaNew Generation	2007	69
Biological Mechanisms of Action of Novel C-10 Non-Acetal Trioxane Dimers in Prostate Cancer Cell Lines Adebusola A. Alagbala, Andrew J. McRiner, Kristina Borstnik, Journal of Medicinal Chemistry Biological MechanismsChemoprevention StrategyMedicineLncap Cell GrowthCell Death	2006	65
Inhibition of hepatitis C virus NS5A by fluoro-olefin based γ-turn mimetics Wonsuk Chang, Ralph T. Mosley, Shalini Bansal, Bioorganic & Medicinal Chemistry Letters γ-Turn MimeticsMedicineDrug DiscoveryAntiviral Drug DevelopmentAntiviral Therapy	2012	60

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