Georgia Cornelius

A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry.

Elizabeth A. Dierks, Karen R. Stams, Heng‐Keang Lim et al. · PubMed · 2001 · 237 citations

Medicine, Pharmacokinetics, Pharmacology +16

DBS Sampling Can be Used to Stabilize Prodrugs in Drug Discovery Rodent Studies without the Addition of Esterase Inhibitors

Celia D’Arienzo, Qin Ji, Lorell Discenza et al. · Bioanalysis · 2010 · 78 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist

Robert J. Cherney, Lyndon A. M. Cornelius, Anurag Srivastava et al. · ACS Medicinal Chemistry Letters · 2020 · 42 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Rationally Designed, Conformationally Constrained Inverse Agonists of RORγt—Identification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy

David Marcoux, James J.‐W. Duan, Qing Shi et al. · Journal of Medicinal Chemistry · 2019 · 37 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P₁ Receptor Modulator in Clinical Trials

T. G. Murali Dhar, Hai‐Yun Xiao, Jenny Xie et al. · ACS Medicinal Chemistry Letters · 2016 · 31 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14