Heng‐Keang Lim

Reproducing human and cross-species drug toxicities using a Liver-Chip

Kyung‐Jin Jang, Monicah A. Otieno, Janey Ronxhi et al. · Science Translational Medicine · 2019 · 474 citations

Pharmacy, Bioengineering, Toxicology +17

The Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of America

Scott Grimm, Heidi J. Einolf, Steven D. Hall et al. · Drug Metabolism and Disposition · 2009 · 306 citations

Medicine, Pharmacokinetics, Pharmacology +17

A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry.

Elizabeth A. Dierks, Karen R. Stams, Heng‐Keang Lim et al. · PubMed · 2001 · 237 citations

Medicine, Pharmacokinetics, Pharmacology +16

Recognition of cell‐wall peptide ligands by vancomycin group antibiotics: Studies using ion spray mass spectrometry

Heng‐Keang Lim, Yin Liang Hsieh, Bruce Ganem et al. · Journal of Mass Spectrometry · 1995 · 116 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Metabolite identification by data‐dependent accurate mass spectrometric analysis at resolving power of 60 000 in external calibration mode using an LTQ/Orbitrap

Heng‐Keang Lim, Jie Chen, Carlo Sensenhauser et al. · Rapid Communications in Mass Spectrometry · 2007 · 115 citations

Life Sciences, Pharmaceutical Analysis, Pharmacology +16