Karen R. Stams

A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry.

Elizabeth A. Dierks, Karen R. Stams, Heng‐Keang Lim et al. · PubMed · 2001 · 237 citations

Medicine, Pharmacokinetics, Pharmacology +16

Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics

Scott Grimm, Neil M. Richtand, Helen Winter et al. · British Journal of Clinical Pharmacology · 2005 · 164 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

Evaluation of Multiple in Vitro Systems for Assessment of CYP3A4 Induction in Drug Discovery: Human Hepatocytes, Pregnane X Receptor Reporter Gene, and Fa2N-4 and HepaRG Cells

Dermot F. McGinnity, George Zhang, Jane R. Kenny et al. · Drug Metabolism and Disposition · 2009 · 89 citations

Medicine, Pharmacokinetics, Pharmacology +15

In vitro prediction of potential metabolic drug interactions for seroquel

Scott Grimm, Karen R. Stams, Khanh Bui · Schizophrenia Research · 1997 · 38 citations

Pharmacy, Pharmacokinetics, Pharmacology +14