Elizabeth A. Dierks

A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry.

Elizabeth A. Dierks, Karen R. Stams, Heng‐Keang Lim et al. · PubMed · 2001 · 237 citations

Pharmacotherapy, Drug Resistance, Probe Substrates +18

Studies of the Heme Coordination and Ligand Binding Properties of Soluble Guanylyl Cyclase (sGC): Characterization of Fe(II)sGC and Fe(II)sGC(CO) by Electronic Absorption and Magnetic Circular Dichroism Spectroscopies and Failure of CO To Activate the Enzyme

Judith N. Burstyn, Anita E. Yu, Elizabeth A. Dierks et al. · Biochemistry · 1995 · 128 citations

Nitric oxide (NO•), the only nitrogen monoxide redox form capable of activating soluble guanylyl cyclase

Elizabeth A. Dierks, Judith N. Burstyn · Biochemical Pharmacology · 1996 · 105 citations

Biochemistry, Reactive Nitrogen Specie, Nitric Oxide +6

Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy

Andrew K. Dilger, Kumar B. Pabbisetty, James R. Corte et al. · Journal of Medicinal Chemistry · 2021 · 93 citations · Full text

Demonstration of the Role of Scission of the Proximal Histidine−Iron Bond in the Activation of Soluble Guanylyl Cyclase through Metalloporphyrin Substitution Studies

Elizabeth A. Dierks, Songzhou Hu, Kathleen M. Vogel et al. · Journal of the American Chemical Society · 1997 · 86 citations

Inorganic Chemistry, Biochemistry, Natural Sciences +14