Lyndon A. M. Cornelius

Discovery of <i>N</i>-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

Louis J. Lombardo, Francis Y. Lee, Ping Chen et al. · Journal of Medicinal Chemistry · 2004 · 1.3K citations · Full text

Drug Target, Preclinical Assays, Pharmacotherapy +19

Discovery of <i>N</i>-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

Gretchen M. Schroeder, Yongmi An, Zhen‐Wei Cai et al. · Journal of Medicinal Chemistry · 2009 · 276 citations · Full text

Orally Efficacious Inhibitor, Drug Target, Pharmacotherapy +21

Synthesis of Cyclobutane-Fused Tetracyclic Scaffolds via Visible-Light Photocatalysis for Building Molecular Complexity

Martins S. Oderinde, Edna Mao, Antonio Ramı́rez et al. · Journal of the American Chemical Society · 2020 · 144 citations

Facile Preparation of 2,6-Disubstituted Purines Using Solid-Phase Chemistry

David A. Nugiel, Lyndon A. M. Cornelius, Jeffrey W. Corbett · The Journal of Organic Chemistry · 1997 · 78 citations

Medicinal Chemistry, Pharmaceutical Science, Natural Sciences +12

DBS Sampling Can be Used to Stabilize Prodrugs in Drug Discovery Rodent Studies without the Addition of Esterase Inhibitors

Celia D’Arienzo, Qin Ji, Lorell Discenza et al. · Bioanalysis · 2010 · 78 citations