Kevin Yang

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 677 citations · Full text

Drug Target, Solid Tumors, Molecular Biology +20

Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors

Noel D. D’Angelo, Tae‐Seong Kim, Kristin L. Andrews et al. · Journal of Medicinal Chemistry · 2011 · 118 citations · Full text

Drug Target, Pharmacotherapy, Benzothiazole Phosphoinositide 3-Kinase +21

Discovery of <i>N</i>-(1-Acryloylazetidin-3-yl)-2-(1<i>H</i>-indol-1-yl)acetamides as Covalent Inhibitors of KRAS^G12C

Youngsook Shin, Joon Won Jeong, Ryan P. Wurz et al. · ACS Medicinal Chemistry Letters · 2019 · 101 citations · Full text

Structure-Based Design of Novel Class II c-Met Inhibitors: 2. SAR and Kinase Selectivity Profiles of the Pyrazolone Series

Longbin Liu, Mark H. Norman, Matthew Lee et al. · Journal of Medicinal Chemistry · 2012 · 74 citations · Full text

Drug Target, Chemical Biology, Pharmaceutical Chemistry +21

Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations

Jing Xu, Kevin Yang, Nancy E. Go et al. · Autophagy · 2022 · 65 citations · Full text